How should this medicine be used?
The combination of amiloride and hydrochlorothiazide comes as a tablet to take by mouth. It usually is taken once a day in the morning with food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take amiloride and hydrochlorothiazide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
This medication controls high blood pressure but does not cure it. Continue to take amiloride and hydrochlorothiazide even if you feel well. Do not stop taking amiloride and hydrochlorothiazide without talking to your doctor.
What special precautions should I follow?
Before taking amiloride and hydrochlorothiazide,
* tell your doctor and pharmacist if you are allergic to amiloride, hydrochlorothiazide, sulfa drugs, or any other drugs.
* tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially captopril (Capoten); digoxin (Lanoxin); enalapril (Vasotec); indomethacin (Indocin); lisinopril (Prinivil, Zestril); lithium (Eskalith, Lithobid); medications for arthritis, diabetes, or high blood pressure; potassium supplements; and vitamins. Do not take this medicine if you are taking spironolactone or triamterene.
* tell your doctor if you have or have ever had diabetes, gout, or kidney or liver disease.
* tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking amiloride and hydrochlorothiazide, call your doctor immediately.
* if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking amiloride and hydrochlorothiazide.
* you should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how this drug affects you.
* remember that alcohol can add to the drowsiness caused by this drug.
What special dietary instructions should I follow?
Follow your doctor's directions for a low-salt or low-sodium diet and daily exercise program. Avoid potassium-containing salt substitutes. Limit your intake of potassium-rich foods (e.g., bananas, prunes, raisins, and orange juice). Ask your doctor for advice on how much of these foods you may have.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
Although side effects from amiloride and hydrochlorothiazide are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away:
* upset stomach
* vomiting
* diarrhea
* loss of appetite
* stomach pain
* gas
* frequent urination
* dizziness
* headache
If you experience any of the following symptoms, call your doctor immediately:
* muscle weakness or cramps
* fatigue
* slow or irregular heartbeat
* sore throat
* unusual bleeding or bruising
* yellowing of the skin or eyes
* skin rash
* difficulty breathing or swallowing
