Aminoglutethimide

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Aminoglutethimide (a-mee-noe-gloo-TETH-i-mide ) acts on a part of the body called the adrenal cortex. It affects production of steroids and also has some other effects. Aminoglutethimide is used to treat some kinds of tumors that affect the adrenal cortex. Also, it is sometimes used when the adrenal cortex is overactive without being cancerous.

Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Some side effects will have signs or symptoms that you can see or feel. Your doctor may watch for others by doing certain tests. Some of the unwanted effects that may be caused by aminoglutethimide are listed below. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare
Black, tarry stools; blood in urine or stools; cough or hoarseness, accompanied by fever or chills; fever or chills; lower back or side pain, accompanied by fever or chills; painful or difficult urination, accompanied by fever or chills; pinpoint red spots on skin; shortness of breath; unusual bleeding or bruising; yellow eyes or skin


Check with your doctor as soon as possible if the following side effects occur:

More common
Drowsiness; measles-like skin rash or itching on face and/or palms of hands


Less common
Clumsiness; dizziness or lightheadedness (especially when getting up from a lying or sitting position); fast heartbeat; mental depression; shakiness; slurred speech; uncontrolled eye movements; unusual tiredness or weakness


Rare
Neck tenderness or swelling


This medicine may also cause the following side effects that your doctor will watch for:

More common
Low red blood cell count; low white blood cell count


Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your health care professional if any of the following side effects continue or are bothersome:

More common
Loss of appetite; nausea


Less common or rare
Deepening of voice in females; headache ; increased hair growth in females; irregular menstrual periods; muscle pain; vomiting


Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.